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After life in a bubble, groundbreaking treatment opens Jakob Guziak’s world

Days after their son was born in 2019, Andrea Fernandez and Kamil Guziak learned their new baby had a rare genetic disease and would be lucky to reach his second birthday.

“You’re thinking, ‘How many pictures can I have with him? How many videos can I create?’” Fernandez says. “Every moment we’re just grabbing for those memories.”

The couple, who live in Canada, learned there was a treatment that could potentially cure their son, Jakob Guziak, but regulatory red tape stood in the way.

A pioneering therapy developed at UCLA Health had proven successful in treating children with the condition Jakob had: ADA-SCID (adenosine deaminase-deficient severe combined immunodeficiency), also known as “bubble baby disease.” However, the treatment had been licensed to a company that stalled before approval from the U.S. Food and Drug Administration and the therapy became unavailable to patients.

https://www.uclahealth.org/news/story/after-life-bubble-groundbreaking-treatment-opens-jakob